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Biomarker Program

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Overview of NACDD Biomarker Program

Program Description:

  This project will build partnerships and collaborations with public health scientific communities, heath care providers, federal departments, universities and private sector organizations.  These partnerships and collaborations will improve the quality of chronic disease biomarker measurements and promote the use of standardized measurements in public health practice, research and clinical care.

Program History: Since 2008 NACDD has worked closely with CDC’s Division of Laboratory Sciences, National Center for Environmental Health. In this capacity we have managed and co-chaired the Cardiovascular Biomarker Standardization Steering Committee and developed translation documents in response to the First and Second "National Reports on Biochemical Indicators of Diet and Nutrition in the U.S. Population” to facilitate dissemination and use of this data. NACDD developed responses to the First (2009) and Second ((2012) "National Reports on Biochemical Indicators of Diet and Nutrition in the U.S. Population.” These reports provide reference intervals for selected nutritional indicators in the U.S. population and our translation responses help integrate the findings into public health practice for prevention and control of chronic disease. In June of 2011, the Cardiovascular Biomarker Standardization Steering Committee (CBSSC), a task force of clinical chemists from universities and private sector laboratories hosted by NACDD and the LSP, met in Atlanta to outline strategic steps towards advancing standardization of laboratory tests for cardiovascular disease. A recent report from the Institute of Medicine (IOM), Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease, has reinforced the need for standardization and the work of the CBSSC.

A cost benefit study sponsored by NACDD and conducted by economists from the Research Triangle Institute was completed in January of 2011. It concluded that the LSP, and a related program the Cholesterol Reference Method Laboratory Network (CRMLN)), showed that standardized cholesterol measuring benefits attributable to these programs prevented or postponed more than 111,000 deaths and saved 1.35 million life-years in 2000 and saved between $338 million and $7.6 billion.

Current Project: Beginning in 2015, NACDD received funding from the CDC to develop a partnership with the Endocrine Society and the Partnership for the Accurate Testing of Hormones (PATH). That partnership resulted in the development of a Strategic Plan and a Communications Plan with a mission to advance the development of standardized hormone assays and to advocate for the universal adoption of these assays in medical practice and research. Six workgroups were originally established to implement recommendations from the Strategic Plans. In 2017, PATH is focused on three key workgroups: Website, Public Outreach and New Member Outreach.

National Association of Chronic Disease Directors
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Decatur, GA 30030
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